A self-loading , self-metering and self-mixing microfluidic reactor array for biochemical screening

A power-free, self-contained microfluidic reactor array is developed for high-throughput analyses. This device needs neither external power nor complex instruments for fluid handling. Thus, it offers an easy-touse and inexpensive way to perform multiple nanoliter-volume distinct reactions in parallel format. We demonstrate the power of this device by testing it for rapid screening of protein crystallization conditions.