Evaluation of applied cases of thrombolytic thera ultra-acute ischemic stroke . py agamst-Using the Japanese Standard Stroke Registry Database

Background: A retrospective evaluation was made concerning thrombolytic therapy for ultra-acute ischemic stroke patients, using a recombinant tissue plasminogen activator (rtPA), which is not yet approved as a drug for brain infarction in Japan. Tlie evaluation was implemented using the database of patients that suffered acute strokes as collected by the Japanese Standard Stroke Registry Study (JSSRS). Methods: The thrombolytic therapy group, selected from among the registered 6,090 cases of brain infarctien patients, was divided into two groups, namely, a group of patients who were admitted in the hospital within S hours of the onset (86 cases, average age 69.6) and the other group who were admitted after 3 hours from the enset {28 cases, average age 66.8). Using a Multiple Logistic Regressien Analysis adapted for modified Rankin scale (mRS) re-