Fibrous liver stiffness analysis using high frequency Magnetic Resonance Elastography at 7 T on an ex vivo rat model . Feasibility and preliminary results

Introduction Multiple studies have reported on developments of hepatic MR Elastography (MRE) to quantitatively assess hepatic fibrosis by measuring the viscoelastic properties of the liver in animal models and humans [1-4]. No recent study has shown a close correlation between ex vivo liver samples and histological semi qualitative quantification of liver fibrosis. The purpose of this study is to evaluate the feasibility of a high-resolution MRE-assessed fibrous liver stiffness analysis in an ex vivo rat model with histological correlation.