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The Suitability of FISH Chromosome Painting and of Tooth Enamel Assays for Retrospective DoseESR-spectroscopyReconstruction

Alexander SEVAN'KAEVi, Igor KHVOSTUNOVi,D. Lloyd,P. Voisin, E. Golub, N. Nadejina,V. Nugis, O. Sidorov, Valeriy SKVORTSOVi BiodosimetryIDicentricsXTranslocationslFISHtESR

semanticscholar(2017)

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Abstract
primary examinations and treatment of the exposed seamen. Cytogenetic analyses were made 16-40 y after their accidents. During medical treatment seven tooth samples were collected fbr ESR analysis from this group. The second group consisted of ten highly irradiated men from the Chernobyl accident. Comparison was made between estimates of their average whole-body penetrating radiation doses derived from several biological parameters. In three cases ESR measurements on tooth enamel from this group were also made. Retrospective dosimetry using FISH tTanslocations was attempted 10-13 y later. Yields of late translocations were in good agreement with initially estimated doses and with doses obtained by ESR spectroscopy analysis of tooth enamel long after exposure. It was concluded that both persisting stable translocations and ESR spectroscopy signals are suitable with similar efficieneies for retrospective biodosimetry after acute whole-body exposure.
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