Exhibits Reduced Gastrointestinal Toxicity as Compared with Naproxen in Arthritic and Aspirin-Treated Rats

Manlio Bolla,Gabriella Coruzzi, Elena Guaita, Giuseppina, Morini,Elena Bastia,Angela Monopoli,Serena Viappiani,John Wallace, Anas Kutait,Sailajah Janarthanan, Zaher, Msallaty,Nishant Tageja, Pascal Kingah,Henry Luma, Elizabeth May

semanticscholar（2018）

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Abstract

Th e Cyclooxygenase-Inhibiting Nitric Oxide Donator (CINOD) Compound NCX 429 Exhibits Reduced Gastrointestinal Toxicity as Compared with Naproxen in Arthritic and Aspirin-Treated Rats Manlio Bolla, PhD,1 Gabriella Coruzzi, PhD,2 Elena Guaita, PhD,2 Giuseppina Morini, PhD,2 Elena Bastia, PhD,3 Angela Monopoli, PhD,3 Serena Viappiani, PhD,1 John Wallace, PhD, MBA4. 1. Scientifi c Aff airs, NicOx SA, Sophia Antipolis, France; 2. Dept. of Human Anatomy, Pharmacology & Forensic Medicine, University of Parma, Parma, Italy; 3. NicOx Research Institute, Bresso (MI), Italy; 4. McMaster University, Hamilton, ON, Canada.

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