In-vitro antioxidative , cytotoxic activity and phytochemical screening from stem bark of Kigelia pinnata

The study was designed to evaluate the phytochemical profile, antioxidant and cytotoxic activity of a methanolic extract from the stem bark of Kigelia pinnata (MEKP). The In-vitro anti-oxidative activity was investigated using DPPH assay, superoxide scavenging assay and cytotoxic activity was studied using cell viability (MTT) assay on non small lung cancer cell-line (A-549). MEKP displayed prominent anti-oxidative and cytotoxic activity against A549 cells. On the basis of the In-vitro studies it could be concluded that there is huge scope for future investigation on K. pinnata as a source of potential anti cancer drug.