Continuing medical education Citrullinated proteins in Rheumatoid Arthritis ☆
semanticscholar(2017)
摘要
Rheumatoid arthritis is an autoimmune disease of multifactorial etiology characterized by inflammation of the joints and presence of autoantibodies directed against multiple autoantigens. Recently the study of the anti-citrullinated protein antibodies (ACP) has acquired great interest due to its high specificity and sensitivity for diagnosis, in addition to which it has shown to be a predictor of severity in patients with rheumatoid arthritis, suggesting an important participation in the pathogenesis of the disease. © 2010 Elsevier España, S.L. All rights reserved. Proteínas citrulinadas en artritis reumatoide
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