Towards the next phase: evaluation of serological assays for diagnostics and exposure assessment.

Corine H. GeurtsvanKessel,NISREEN M.A. OKBA,Zsofia Igloi,Carmen W.E. Embregts,Brigitta M. Laksono,Lonneke Leijten,Janette Rahamat-Langendoen,Johannes P.C. van den Akker,Jeroen J.A. van Kampen,Annemiek A. van der Eijk,Rob S. van Binnendijk,Bart Haagmans,Marion Koopmans

medRxiv（2020）

引用 39|浏览22

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摘要

The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the deployment of serology for either population screening or diagnostics, we present a comprehensive comparison of serological COVID-19 assays. We show that the assay detecting total immunoglobulins against the receptor binding domain of SARS CoV-2, had optimal characteristics for antibody detection in different stages of disease.

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关键词

serological assays,diagnostics,exposure,assessment

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