Viral Shedding Prolongation In A Kidney Transplant Patient With Covid-19 Pneumonia

Zhang Man, Zhang Jing,Shi Huibo,Liu Bin,Zeng Fanjun

AMERICAN JOURNAL OF TRANSPLANTATION(2020)

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摘要
Coronavirus disease 2019 (COVID-19) pandemic sweeps the globe. The information regarding the kinetic changes of SARS-CoV-2 in immunosuppressed patients is unclear. Herein, we present a case of prolonged viral shedding in a transplant patient with COVID-19 pneumonia. A 49-year-old male kidney recipient was admitted to the hospital on February 7, 2020, for fever and fatigue. He was a permanent resident in Wuhan, China, and began having symptoms on January 29 (day 1 of illness). His maintenance immunosuppressive regime was consisted of tacrolimus (TAC, 1mg twice a day, orally), mycophenolate mofetil (MMF, 0.5g twice a day, orally) and prednisone (Pred, 5mg daily, orally) triple combination.
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关键词
clinical research,practice,immunosuppressant,immunosuppression,immune modulation,infection and infectious agents - viral,infectious disease,kidney disease,infectious,kidney transplantation,nephrology
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