Clinical observation of different treatment strategies in pregnant women with COVID-19: a retrospective study

Research Square(2020)

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摘要
Abstract Objective: this study aimed to clarify the clinical characteristics, obstetrical and fetal outcomes of patients with Corona Virus Disease 2019 (COVID-19) in different stage during pregnancy.Methods: 13 pregnant women with COVID-19 were admitted to Wuhan central hospital and Renmin hospital of Wuhan university between Jan 20 and march 20, 2020, including four patients in first and second trimester demanding for pregnancy termination, seven in first and second trimester and two in third trimester keeping pregnancy. The two groups’ clinical characteristics, treatment and maternal and fetal outcomes were observed and analyzed.Results: Most common clinical manifestation were fever and cough. Among the patients keeping pregnancy, one had a spontaneous miscarriage and fetal malformation was found in another one. Two patients who had a vaginal delivery presented good maternal and neonatal outcomes. All patients showed a good recovery. Conclusion: SARS-COV-2 infection could cause spontaneous miscarriage and fetal malformation in early pregnancy.
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