First cured patient with 2019 novel coronavirus in Changsha, China, a case report

Abstract Background: In December, 2019, the novel coronavirus (2019-nCoV) firstly occurred in Wuhan, Hubei Province, China. It spreads rapidly and many cases are identified in multiple countries, which pose a great threat to people's health. Here we report the first cured patient with 2019-nCoV infection in Changsha, China, and the symptoms, diagnosis, treatment and management of this patient are all described in the present study. Case presentation: A 57 year old woman developed cough and fever after returning from Wuhan to Changsha on January 9, 2020. She was tested positive for 2019-nCoV infection, which was supported by Chest CT. Lopinavir and ritonavir tablets and interferon alfa-2b injection were used for treatment. A small dose of glucocorticoids were used in a short period to control the immune response in bilateral lung and this patient avoided the occurrence of cytokine storms. The clinical condition of this patient improved and negative result was obtained for 2019-nCoV assay on January 25, 2020. This patient was recovered and discharged on January 30, 2020. Conclusions: At present, many reports about 2019-nCoV infection focused on the epidemiological and clinical characteristics of this disease. This case described the symptoms, diagnosis, treatment and management of a cured patient with 2019-nCoV infection, which may provide information for the treatment of 2019-nCoV infection.