Chrome Extension
WeChat Mini Program
Use on ChatGLM
VIPCreated with Sketch.

Design, synthesis and biological evaluation of novel 2-alkylidene 19-norcalcitriol analogs.

Adrian Fabisiak,Pawel Brzeminski,Klaudia Berkowska,Lucie Rárová,Ewa Marcinkowska,Rafal R Sicinski

Bioorganic Chemistry（2020）

Cited 1|Views27
No score
Abstract
•Series of 19-norcalcitriol analogs with pegylated 2-alkylidene groups were synthesized.•Pt(II) complexes of two vitamin D analogs were obtained and biologically tested.•Cytotoxic activity of the synthesized 19-norcalcitriol analogs was assessed.
More
Translated text
Key words
19-Norcalcitriol,Vitamin D receptor,Wittig-Horner reaction,Platinum(II) complexes,Drug delivery systems
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined