Lappaconitine sulfate induces apoptosis and G0/G1 phase cell cycle arrest by PI3K/AKT signaling pathway in human non-small cell lung cancer A549 cells.

Danni Qu,Junyi Ma,Na Song,Ling Hui,Lihua Yang,Yongyue Guo,Chunyan Sang

Acta Histochemica（2020）

引用 12|浏览5

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摘要

•Lappaconitine sulfate (LS) has anti-proliferative activity in A549 cells.•LS can induce apoptosis and G0/G1 phase cell cycle arrest by PI3K/AKT pathway.•LS may be a novel effective candidate for the treatment of A549 cells.

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LA,LS,LH,CCK-8,PBS,FTIR,OD,EdU,SDS-PAGE,PVDF

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