Precise imaging of mitochondria in cancer cells by real-time monitoring of nitroreductase activity with a targetable and activatable fluorescent probe.

Ning Zhu,Ge Xu,Rongchen Wang,Tianli Zhu,Jiahui Tan,Xianfeng Gu,Chunchang Zhao

CHEMICAL COMMUNICATIONS（2020）

引用 31|浏览3

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摘要

An activatable and mitochondrial-targetable fluorescent probe was developed. This designed probe showed ratiometric fluorescence and light-up near-infrared emission responsiveness to nitroreductase, achieving precise imaging of mitochondria in cancer cells by real-time monitoring of nitroreductase activity.

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