Retinal Nerve Fibre Layer Thickness Change After Co2 Laser-Assisted Deep Sclerectomy Surgery

Purpose: The goal of our study was to investigate changes in intraocular pressure (IOP), best -corrected visual acuity (BCVA), and retinal nervebre layer thickness (RNFLT) after CO2 laser -assisted deep sclerectomy (CLASS). Methods: We carried out uncomplicated CLASS surgeries and a 12 -month follow-up on 22 open -angle glaucomatous (OAG) eyes of 22 patients. IOP, BCVA, and RNFLT with spectral -domain optical coherence tomography (SD OCT) were recorded before and 1, 3, 6, 12 months after surgery. Results: Mean age of patients was 68.1 years. IOP decreased from preoperative 28.45+/-5.99 SD mmHg (mean+/-standard deviation) to 15.09+/-2.40 mmHg (p=0.00039) at 12 months after surgery. BCVA-change from preoperative 0.34+/-0.38 SD (LogMAR) to 0.37+/-0.41 SD (LogMAR) was not signicant (p=0.2456). RNFLT-change from preoperative 60.50 +/-18.15+/-m to 59.63+/-17.52 +/-m at 12 months postoperatively was not signicant (p=0.056). Qualied success rate of CLASS surgery was 72.7%, whereas complete success rate was 64% at 1 year postoperatively. Conclusion: Successful CLASS surgery efficiently reduced IOP. At postoperative 12 months, RNFLT and BCVA were not reduced signicantly. There was no signicant glau-comatous progression after surgery encountered in respect of investigated parameters.