Genomic Discovery of an Evolutionarily Programmed Modality for Small-Molecule Targeting of an Intractable Protein Surface
Uddhav K. Shigdel,Seung-Joo Lee,Mathew E. Sowa,Brian R. Bowman,Keith Robison,Minyun Zhou,Khian Hong Pua, Dylan T. Stiles,Joshua A. Blodgett,Daniel W. Udwary,Andrew T. Rajczewski,Alan S. Mann,Siavash Mostafavi,Tara Hardy,Sukrat Arya,Zhigang Weng,Michelle Stewart, Kyle Kenyon,Jay P. Morgenstern, Ende Pan,Daniel C. Gray, Roy M. Pollock,Andrew M. Fry,Richard D. Klausner,Sharon A. Townson,Gregory L. Verdine Proceedings of the National Academy of Sciences（2020）
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natural products,genome mining,FK506-binding protein
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