Outcomes Of Reflex Cryptococcal Antigen (Crag) Screening In Human Immunodeficiency Virus (Hiv)-Positive Patients With Cd4 Counts Of 100-200 Cells/Mu L In Botswana

CLINICAL INFECTIOUS DISEASES(2021)

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Abstract
Increasing the CD4-count threshold for cryptococcal antigen (CrAg) screening from <= 100 to <= 200 cells/mu L resulted in a 3-fold increase in numbers screened. CrAg-prevalence was 3.5% at CD4 101-200 and 6.2% <= 100 cells/mu L. Six-month mortality was 21.4% (9/42) in CrAg-positive CD4 <= 100 cells/mu L and 3.2% (1/31) in CrAg-positive CD4 101-200 cells/mu L.
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Key words
advanced HIV, HIV/AIDS, cryptococcal antigen, antiretroviral therapy, HIV treat all
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