The Role of Acid-sensing Ion Channel 3 in the Modulation of Tooth Mechanical Hyperalgesia Induced by Orthodontic Tooth Movement
Neuroscience（2020）
Abstract
•Acid-sensing ion channel 3 modulates tooth movement-induced mechanical hyperalgesia.•Trigeminal ganglia regulates ASIC3-mediated pain modulation in periodontal tissues.•Therapies targeting ASIC3 can manage tooth movement-induced mechanical hyperalgesia.
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Key words
ANOVA,ASIC3,CGRP,IAN,NeuN,PCR,TG
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