Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy

Kamal S. Saini, Carlo Lanza,Marco Romano,Evandro de Azambuja,Javier Cortes,Begoña de las Heras,Javier de Castro,Monika Lamba Saini,Sibylle Loibl,Giuseppe Curigliano,Chris Twelves,Manuela Leone,Mrinal M. Patnaik

BRITISH JOURNAL OF CANCER（2020）

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摘要

Summary Three cardinal manifestations of neoplasia, namely inflammation, immune dysfunction, and coagulopathy are also seen in patients with severe SARS-CoV-2 infection, providing a biological rationale for testing selected anticancer drugs for their ability to control the symptoms and/or modify the course of COVID-19.

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Drug development,Viral infection,Biomedicine,general,Cancer Research,Epidemiology,Molecular Medicine,Oncology,Drug Resistance

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