Synergistic effect of combined imipenem and photodynamic treatment with the cationic Ir(III) complexes to polypyridine ligand on carbapenem-resistant Klebsiella pneumoniae
Photodiagnosis and Photodynamic Therapy(2020)
摘要
•The Photodynamic treatment helped to eradicate the MDR bacteria Klebsiella pneumoniae•Photosensitizers based in Ir(III) are useful for aPDI over KPC producer Klebsiella pneumoniae.•Ir(III) PS produces a synergistic effect with imipenem against KPC-producer Klebsiella pneumoniae.•Ir(III) PS produced no cytotoxicity over normal cells but produce light-activated cytotoxicity over tumoral cells.
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关键词
Antibiotic resistance,Photodynamic treatment,Synergy,Klebsiella pneumoniae
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