Central Visual Field Loss Patterns In Glaucoma

Methods: Total deviation values from reliable 10-2 VFs from 5 academic glaucoma services in the US were used to determine the CVF loss patterns for eyes with all glaucoma severities using the most recent 10-2 VFs. Furthermore, the CVF loss patterns were identified for mild, moderate and severe glaucoma separately. The 10-2 VFs tested within 3 months of or before any 24-2 VF with mean deviation (MD)≥-6 dB were assigned to mild glaucoma, were assigned to severe glaucoma if tested within 3 months of or after any 24-2 VF with MD<-12 dB, and were assigned to moderate glaucoma if they were tested within 3 months of or between 24-2 VFs with-12 dB≤ MD<-6 dB. The most recent 10-2 VFs of each eye were selected for each glaucoma stage. An unsupervised machine learning method of archetypal analysis was applied to determine the CVF loss patterns. Cross-validation was performed to determine the …