Research on the mechanism of Chinese herbal medicine Radix Paeoniae Rubra in improving chronic pelvic inflammation disease by regulating PTGS2 in the arachidonic acid pathway.

Xiao-Hong Li,Yan-Ru Liu,Da-Hai Jiang,Zhi-Shu Tang,Da-Wei Qian,Zhong-Xing Song,Lin Chen,Xin-Bo Shi,Ning-Juan Yang,Ya-Feng Yan,Ai-Bing Chang

Biomedicine & Pharmacotherapy（2020）

引用 13|浏览21

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摘要

•PTGS2 may be a potential therapeutic target for pelvic inflammation disease (CPID).•RPR attenuates uterine inflammation in CPID rats by downregulating PTGS2 expression.•RPR can treat CPID by acting on the arachidonic acid pathway.

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关键词

RPR,CPID,PTGS2,AA,PG,WB,PCR,HE,ELISA,TNF-α,IL-2,OD,GO,BP,MF,CC,KEGG,IDA,DP,CE,CES,TEM,DAB,PBS,BSA,ECL,PVDF,WBC,ALT,ALP,AST,TBA,GLU,CREA,UA,TP,ALB,TC

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