Vexin is upregulated in cerebral cortical neurons by brain-derived neurotrophic factor.

Hisatsugu Koshimizu,Shingo Suzuki,Anna Kawai,Ryuichiro Miura,Ken-Ichi Ohta,Takanori Miki,Naoki Adachi,Hidetada Matsuoka

Neuropsychopharmacology reports（2020）

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摘要

The upregulated H3K27ac in the brain may be associated with the enriched gene expression of Vexin in the brain. It is indicated that BDNF induces the gene expression of Vexin in the cortical neurons via the TrkB-MEK signaling pathway.

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关键词

H3K27ac,Vexin,brain-derived neurotrophic factor,cultured cortical neurons

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