1 H, 13 C, and 15 N backbone assignments of the C-terminal region of the human retinoic acid-induced protein 2

Retinoic acid-induced protein 2 is a human protein of 530 residues encoded by the RAI2 gene (Q9Y5P3; RAI2_HUMAN). RAI2 is a novel tumor suppressor protein whose depletion in breast cancer cell lines results in the downregulation of several genes associated with differentiation along with increased invasiveness and aggressive tumor phenotype of the cells. The role of the protein is specified to be a transcriptional regulator that promotes chromosomal stability and hence controls the expression of several regulators of cancer and metastasis. Structurally, RAI2 remains an unknown entity and, hence, to obtain a detailed view on the structure function relationship we report the 1 H, 13 C, and 15 N resonance assignments for the backbone and side chain nuclei of the C-terminal region (a.a. 303–451 of UniProt Q9Y5P3) of RAI2.