Apigenin, flavonoid component isolated from Gentiana veitchiorum flower suppresses the oxidative stress through LDLR-LCAT signaling pathway.

•Apigenin is identified as the most abundant flavonoid in the extraction of Gentiana veitchiorum flower.•The isolated apigenin exhibits radical scavenging activities.•The isolated apigenin suppressed the high fat diet-induced oxidative damage in hyperlipidemic rats.•The effects of apigenin on the reduction of lipidic deposition is achieved via LDLR-LCAT signaling pathway.