Apigenin, flavonoid component isolated from Gentiana veitchiorum flower suppresses the oxidative stress through LDLR-LCAT signaling pathway.
Biomedicine & Pharmacotherapy(2020)
Abstract
•Apigenin is identified as the most abundant flavonoid in the extraction of Gentiana veitchiorum flower.•The isolated apigenin exhibits radical scavenging activities.•The isolated apigenin suppressed the high fat diet-induced oxidative damage in hyperlipidemic rats.•The effects of apigenin on the reduction of lipidic deposition is achieved via LDLR-LCAT signaling pathway.
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Key words
Gentiana veitchiorum,Flavonoid,Apigenin,Antioxidant,LDLR-LCAT pathway
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