Molecular cloning of crustacean hyperglycemic hormone (CHH) family members (CHH, molt-inhibiting hormone and mandibular organ-inhibiting hormone) and their expression levels in the Jonah crab, Cancer borealis.

•The following cans are isolated from eyestalk ganglia [CHH, molt-inhibiting hormone (MIH), and mandibular organ-inhibiting hormone (MOIH)]; pericardial organ (CHH); and stomatogastric nervous system (STNS) [CHH, MIH, and MOIH].•The presence of CHH, MIH, and MOIH in the male sinus gland; female is also containing crustacean female sex hormone (CFSH).•All three neuronal tissues contain the same CHH isoform; STNS also includes an additional PO-type CHH.•The levels of transcripts in eyestalk ganglia are related to the respective neuropeptide contents in sinus gland.