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Mn-TAT PTD-Ngb ameliorates inflammation through the elimination of damaged mitochondria and the activation of Nrf2-antioxidant signaling pathway.

Cui Zhang, Ruirui Yang,Xuehui Hao,Zhirong Geng,Zhilin Wang

Biochemical Pharmacology（2020）

Cited 10|Views8
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Abstract
Mn-TAT PTD-Ngb attenuated the inflammatory response and the activation of the NLRP3 inflammasome. Mn-TAT PTD-Ngb enhanced the intracellular antioxidant system and eliminated mitochondrial oxidative stress better than TAT PTD-Ngb.
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Key words
Mn-TAT PTD-Ngb,ROS,Inflammatory response,Nrf2,NLRP3
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