Systematic Review and Meta-Analysis on the Associations of Polypharmacy and Potentially Inappropriate Medication with Adverse Outcomes in Older Cancer Patients.

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY(2020)

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摘要
Polypharmacy was found to be associated with several adverse outcomes and PIM use with all-cause mortality in older cancer patients. However, these results should be interpreted with caution because about three-quarters of the studies identified did not adjust for comorbidity and are prone to confounding by indication.
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关键词
Adverse Drug Reaction,Geriatric Oncology,Hospitalizations,Mortality,Postoperative Complications
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