Perinatal selective serotonin reuptake inhibitor exposure and behavioral outcomes: a systematic review and meta-analyses of animal studies.

A.S. Ramsteijn,L. Van de Wijer,J. Rando,J. van Luijk,J.R. Homberg,J.D.A. Olivier

Neuroscience & Biobehavioral Reviews（2020）

引用 28|浏览8

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摘要

•Perinatal SSRIs alter activity, stress coping, and sensory processing in rodents.•Fewer females than males are studied in regards to early SSRI exposure.•Females appear less affected by perinatal SSRIs than males.•SSRIs have the largest effects in rodents after early postnatal exposure.•More animal models of perinatal depression and SSRI use are needed.

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关键词

Activity and exploration,Animal studies,Antidepressants,Anxiety,Behavior,Developmental exposure,Ingestive and reward behavior,Learning and memory,Meta-analysis,Motoric behavior,Offspring,Pregnancy,Reflex and pain sensitivity,Selective serotonin reuptake inhibitors (SSRIs),Sensory processing,Sleep and circadian activity,Social behavior,Stress coping,Systematic review,Teratogenic effects

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