Experimental evidence for alpha enolase as one potential autoantigen in the pathogenesis of both autoimmune thyroiditis and its related encephalopathy.

Yihan Lu,Juan Qin,Yang Xiang,Rongli Sun,Yan Feng,Hongmei Zhang, Shuangning Ding,Jing Li,Zhongyan Shan,Weiping Teng

International Immunopharmacology（2020）

引用 8|浏览16

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摘要

•ENO1Ab can cause thyrocyte damage through ADCC effect via CD16+ NK cells.•ENO1Ab can cause cognitive dysfunction by disrupting the blood-brain barrier.•ENO1Ab may be the pathogenic antibody during AIT and its related encephalopathy.

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关键词

α-Enolase,Autoimmunity,Thyroiditis,Encephalopathy

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