Elevated neopterin levels are associated with acute-on-chronic liver failure and mortality in patients with liver cirrhosis.

Camila Matiollo,Elayne Cristina de Moraes Rateke, Karina Ghisoni de Oliveira,Bruna Lenfers Turnes,Telma Erotides da Silva,Claudia Maccali,Alexandra Susana Latini,Janaína Luz Narciso-Schiavon,L L Schiavon

Digestive and Liver Disease（2020）

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摘要

Higher circulating neopterin was associated with ACLF in patients hospitalized for AD of cirrhosis. Neopterin levels were also independently predictors of high short-term mortality, especially among patients with ACLF, and could represent a useful biomarker of macrophage activation in clinical practice.

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关键词

Acute decompensation,Acute-on-chronic liver failure,Liver cirrhosis,Neopterin

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