Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination.

Ramona Mögling,Adam Meijer, Natasa Berginc,Sylvia Bruisten,Remi Charrel,Bruno Coutard,Isabella Eckerle,Vincent Enouf,Olav Hungnes,Gülay Korukluoglu,Thanos Kossyvakis,Andreas Mentis,Richard Molenkamp,Shaman Muradrasoli,Anna Papa,Fiona Pigny,Laurence Thirion,Sylvie van der Werf,Chantal Reusken

EMERGING INFECTIOUS DISEASES（2020）

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摘要

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe simultaneously implemented SARS-CoV-2 diagnostics. These laboratories reported in February 2020 that commercial primer and probe batches for SARS-CoV-2 detection were contaminated with synthetic control material, causing delays of regional testing roll-out in various countries.

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关键词

COVID-19,Europe,PCR,SARS-CoV-2,commercial nucleotide production,contamination,coronavirus disease,coronaviruses,delayed laboratory response,molecular diagnostics,primers,probes,respiratory infections,severe acute respiratory syndrome coronavirus 2,viruses,zoonoses

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