In utero exposure to arsenite contributes to metabolic and reproductive dysfunction in male offspring of CD-1 mice

Karina F. Rodriguez,Namya Mellouk,Erica K. Ungewitter,Barbara Nicol,Chang Liu,Paula R. Brown,Cynthia J. Willson,Humphrey H.-C. Yao

Reproductive Toxicology（2020）

Cited 10|Views9

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Abstract

•In utero exposure to arsenite resulted in obesity phenotypes in male mice.•In utero exposure to arsenite had minimal impact on reproductive phenotype in male mice.•These changes were observed at 10 ppb and 42.5 ppm of arsenite in the drinking water.

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Key words

Arsenic,Developmental origins of health and diseases,In utero exposure,Metabolic syndromes,Obesity

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