Peptidomic analysis on synovial tissue reveals galectin-1 derived peptide as a potential bioactive molecule against rheumatoid arthritis.

Cytokine(2020)

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摘要
•We aimed to reveal pathogenesis of RA in peptidomic perspective.•Bioinformatics analyses disclosed the roles of differentially peptides in RA.•A galectin-1 derived peptide inhibited abnormal proliferation of synovial cells.
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关键词
Bioactive peptide,Peptidomics,MH7A,LC-MS/MS,Synovial fibroblast,Inflammatory,TNF-α
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