Src family kinases and pulmonary fibrosis: A review

Hang Li,Caiping Zhao, Ye Tian,Juan Lu,Guiyu Zhang,Shuang Liang,Dongfeng Chen,Xiaohong Liu,Weihong Kuang,Meiling Zhu

Biomedicine & Pharmacotherapy（2020）

引用 43|浏览8

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摘要

•Summarize the pathogenesis of IPF.•Summarize the structure and function of Src family kinases.•Summarize the role of Src family kinases in pulmonary fibrosis.•Summarize targeting Src family kinases strategies, including inhibitors and microRNA, and their effect on the pathophysiology of pulmonary fibrosis.

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关键词

Src family kinase,Pulmonary fibrosis,Myofibroblast activation,Epithelial-mesenchymal transition,Inflammation

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