Cytokine stimulation of the choriocarcinoma cell line JEG-3 leads to alterations in the HLA-G expression profile.

Gry Persson, Julie Birgit Siig Bork,Cecilie Isgaard,Tine Graakjær Larsen, Anna Maria Bordoy, Meghan Sand Bengtsson,Thomas Vauvert Faurschou Hviid

Cellular Immunology（2020）

引用 17|浏览7

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摘要

•Proinflammatory cytokines downregulate human leukocyte antigen-G on JEG-3 cells.•Interferon-γ may play a role in maintenance of human leukocyte antigen-G expression.•Interleukin-10 may be involved in regulation of human leukocyte antigen-G isoforms.•The local cytokine profile is important for human leukocyte antigen-G expression.

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关键词

HLA-G,PE,APC

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