The chimeric antigen receptor-intensive care unit (CAR-ICU) initiative: Surveying intensive care unit practices in the management of CAR T-cell associated toxicities

Journal of Critical Care(2020)

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摘要
•Despite the high acuity of illness of CRS and ICANS, there is limited data in its ICU management•The CAR-ICU (11 leading institutions within the US) focuses on studying critically ill CAR T-cell patients•Our survey reports the structure and practices of care for CAR patients in different ICUs•Practices in the management of CAR T-cell patients varies within institutions in the US•We identify areas of future research that could impact outcomes of critically ill CAR T-cell patients.
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关键词
Chimeric antigen receptor T-cell,Cytokine release syndrome,Immune effector cell associated neurotoxicity syndrome,Intensive care unit,Toxicities,CAR-ICU
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