Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish.
Environment International（2020）
Abstract
•Combined effects of MPs and BHA on zebrafish embryos/larvae were evaluated.•MPs promoted the accumulation of BHA in zebrafish larvae.•MPs enhanced the toxicity of BHA in larvae development.•Coexposure disturbed arachidonic acid, glycerophospholipid, and lipids metabolism.
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Key words
Microplastics,Antioxidants,Coexposure,Developmental toxicity,Zebrafish,Metabolomics
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