High-sensitivity microliter blood pressure sensors based on patterned micro-nanostructure arrays.

Herein we present a micro-nanostructure integrated liquid pressure sensor, which features an ultra-high sensitivity of 16.71 mbar(-1), a low-pressure regime of 2 mbar, a trace sample volume of less than 1.3 mu L and a visible display element. The measurable pressure ranges of the sensors include not only from micro-scale fluids to bulk liquids but also from hydraulic pressures to blood pressures, opening a window for liquid pressure sensing in lab-on-chip platforms, point-of-care diagnostics, and even robotics.