Linc-FOXD3 knockdown enhances hippocampal NSCs activation through upregulation of the Wnt/β-catenin pathway.
Neuroscience Letters（2020）
Abstract
•The proliferation and neuronal-differentiation capacities of H-NSCs reduced with aging.•Linc-FOXD3 was significantly upregulated in aged H-NSCs.•Linc-FOXD3 knockdown in H-NSCs promotes their proliferation and neuronal-differentiation.•Linc-FOXD3 knockdown in H-NSCs activiates Wnt/β-catenin pathway.
MoreTranslated text
Key words
Hippocampus,NSCs,lincRNAs,β-catenin
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined