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The Role of Non-Glycolytic Glucose Metabolism in Myocardial Recovery Following Mechanical Unloading and Circulatory Support in Chronic Heart Failure

R. Badolia,D.K. Ramadurai,I. Taleb,T. Shankar,A. Thodou,M. Yin,S. Navankasattusas,A. Kfoury,R. Alharethi, W. Caine,O. Wever-Pinzon,J. Fang,C. Selzman, J. Stehlik,S. McKellar, S. Drakos

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2020）

Cited 37|Views97
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Abstract
The recovering human heart appears to direct glycolytic metabolites into the PPP and OCM pathways which could contribute to cardioprotection and improved myocardial function by generating NADPH to enhance biosynthesis for repair and by reducing oxidative stress.
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Key words
myocardial recovery,glucose,circulatory support,metabolism,non-glycolytic
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