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T-tubule disruption is a prominent feature of HFrEF but not HFpEF

Michael Frisk,Christopher Le,Yufeng Hou,Åsmund Røe,Christen Dahl,Xin Shen,Ivar Sjaastad,Ida Lunde,Lars Gullestad,Theis Tønnessen,Ole Sejersted,Peter Jones,William Louch

Journal of Molecular and Cellular Cardiology（2020）

Cited 0|Views18
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Abstract
Heart failure comprises two main entities; heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF), which both results from severe left ventricular remodeling. Whereas HFpEF is commonly caused by concentric hypertrophy and stiffening of the ventricular wall, HFrEF results from chamber dilation, wall thinning and reduced pump capacity.
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Postinfarction Ventricular Septal Defect
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