Methane-Enriched Custodiol Preservation Solution Improves Graft Function in Experimental Model of Heterotopic Heart Transplantation

K. Benke,M. Ruppert, A.A. Sayour, D. Jász, Á. Szilágyi, E. Tuboly, B. Baráth, A. Márton,M. Boros,P. Hartmann, G. Szabo, I. Hartyánszky, Z. Szabolcs,B. Merkely,T. Radovits

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2020）

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摘要

These results might provide reliable evidence for the benefit of CH-enriched preservation solution during HTX, through a mechanism which involves the inhibition of pro-apoptotic signals. Hence CH-enriched preservation solution could be a potential cardioprotective agent in the inventory of heart transplantation surgery and other cardiac surgical procedures requiring prolonged cardioplegia.

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