Medical Applications of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas) Tool: A Comprehensive Overview.

Rodrigo Pinheiro Araldi,Charbel Khalil, Pedro Henrique Grignet,Michelli Ramires Teixeira,Thatiana Correa de Melo,Diego Grando Módolo,Luis Guilherme Virgílio Fernandes,Jorge Ruiz,Edislane Barreiros de Souza

Gene（2020）

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摘要

•Rediscovery of CRISPR/Cas system has revolutionized the gene editing field.•The variety of CRISPR/Cas systems allows many different approaches.•The CRISPR/Cas system shows a potential for both basic and translational research.•Studies are crucial to guarantee the biosafety of CRISPR/Cas for clinical purpose.

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关键词

CRISPR/Cas9,Gene editing,Personalized medicine,Technical recommendations, medical applications

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