Predictors and Outcomes of Hemodynamic and Functional LVAD Non-Responders: An Analysis of the INTERMACS Registry

Up to 40% of patients with post-implant hemodynamics were non-responders to LVAD therapy in important HF domains. Pre-implant age, high BMI, device type, elevated BUN, and presence of CRT device were associated with hemodynamic and functional NR. Future research is warranted to understand whether LVAD non-responsiveness can be modified with device modification and/or medical therapy.