Enhancing the Anticancer Activity and Selectivity of Goniothalamin Using pH-Sensitive Acetalated Dextran (Ac-Dex) Nanoparticles: A Promising Platform for Delivery of Natural Compounds

Carolyne Brustolin Braga,Larissa A. Kido,Ellen N. Lima,Celina A. Lamas,Valéria H. A. Cagnon,Catia Ornelas,Ronaldo A. Pilli

ACS Biomaterials Science & Engineering（2020）

引用 16|浏览6

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摘要

Goniothalamin (GTN), a natural compound isolated from Goniothalamus species, has previously demonstrated cytotoxic activity against several cancer cell lines. However, similarly to many natural and...

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关键词

goniothalamin,Ac-Dex,pH-responsive polymeric nanoparticles,drug delivery,cancer therapy,nanomedicine

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