Uncovering Salient Cellular Heterogeneity in Human Lung Transplantation Using Single-Cell RNA Sequencing

Using scRNAseq, we offer insights into the cellular composition of stable and AR BAL and created a map of tissue-resident cells in a CLAD lung. Further application of this powerful tool is underway and will deepen our understanding of the cellular complexity of LT immunobiology and its role in allograft injury and dysfunction.