SAT-445 ASSESSMENT OF MICROALBUMINURIA AND ITS CLINICAL AND BIOCHEMICAL CORRELATES IN INDIVIDUALS WITH SICKLE CELL GENE

Sickle Cell Disease (SCD) is a major genetic disease noted to be prevalent in most countries in Sub-Saharan Africa. Patients with SCD may develop a glomerulopathy with proteinuria and progressive renal insufficiency, leading to end stage renal disease (ESRD) with consequent need for renal replacement therapy. Microalbuminuria (MA) has been shown to be an early predictor of Nephropathy in SCD.