Esi-Tof Ms Analysis And Dna Cleavage Activity Of Complexes Formed By Luteolin And Five Metal Ions In Hot Water
INORGANIC AND NANO-METAL CHEMISTRY(2020)
摘要
Luteolin is a common flavonoid in plants and exhibits a variety of biological activities. In this study, luteolin was reacted in hot water with five trace metal elements found in plants, and the products were tested by electrospray-ionization time-of-flight mass spectrometry (ESI-TOF MS). Luteolin formed complexes with Ca2+, Mg2+, and Zn2+ in both 2:1 and 3:1 ratios, in addition to a complex with Cu2+ in a 2:1 ratio. A luteolin-iron (III) complex was also formed in a 2:1 ratio, and a small amount of Fe2+ was produced to form a luteolin-iron (II) complex in a 2:1 ratio. The formed luteolin-Cu2+ complex exhibited significant DNA cleavage activity in a time- and concentration-dependent manner, while no or little such activity was observed for luteolin or Cu2+ alone. Therefore, complexes of luteolin and trace metal elements may exist in cooked foods and medicinal plant decoctions, which could influence associated health and therapeutic effects.
更多查看译文
关键词
Luteolin, hot water, metal complex, ESI-TOF MS, DNA cleavage, flavonoid
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要