Indoxyl Sulfate Is A Key Player In The Cardiorenal Anemia Syndrome And Predicts The Clinical Outcome After Acute Decompensated Heart Failure

Ippei Watanabe,Junko Tatebe,Takahiro Fujii,Hideki Koike,Takanori Ikeda,Toshisuke Morita

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2020）

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摘要

The cardiorenal anemia syndrome is a prognostic factor in patients with heart failure. However, little has been investigated whether circulating uremic toxins impact in the underlying mechanism. Indoxyl sulfate (IS), a protein bound uremic toxin is known to suppress hemotopoietic capacity with

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cardiorenal anemia syndrome,heart failure,clinical outcome

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